Gene Analysis (5, 10-Methylenetetrahydrofolate Reductase) Common Variants in Colorado

Colorado Pricing in Context

In Colorado, CPT code 81291 (Gene Analysis (5, 10-Methylenetetrahydrofolate Reductase) Common Variants) carries an average Medicare payment of $64.03 — 0% above the national benchmark of $63.93. 3 providers across the state submitted claims for this procedure in 2023, performing 131 total services. Individual payments in CO ranged from N/A at the low end to N/A at the high end, reflecting differences in provider setting (office vs. facility), modifiers, and the specific geographic locality code applied within the state.

The average billed charge in Colorado is $348.83, which is the figure uninsured patients would most likely encounter before any negotiation or charity discount. Medicare, by statute, only reimburses the allowed amount — the balance between billed and paid is written off under provider participation agreements. Insured patients generally pay a negotiated rate that falls between these two figures; the exact amount depends on plan design, deductible status, and in-network participation. Because Colorado sits above the national Medicare average, commercial rates in the state may also run higher than the US median.

Using RAND 2024 commercial-to-Medicare ratios for Genetic/Molecular Test procedures, the estimated commercial insurance price in Colorado lands near $147.27, with self-pay cash prices typically around $143.95. Before scheduling, patients can request a Good Faith Estimate under the No Surprises Act, compare cash rates from hospital Machine-Readable Files, and confirm whether the provider is in-network with their specific plan. This page presents CMS reference data for informational use; it does not constitute medical or financial advice.