CMS 2023 data Official source Free · public domain

Vaccines & Injections

91 procedures in Vaccines & Injections. Medicare reimbursement averages $65.01 per service; billed charges average N/A. Source: CMS Medicare Physician & Other Practitioners 2023.

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Where this category sits

Among CMS procedure categories, Vaccines & Injections ranks #51 of 73 by average Medicare payment ($65.01 per service across its 91 procedure codes).

#51
of 73 categories by avg payment
$65.01
avg Medicare payment
91
procedure codes

Category placement is ordered by average Medicare payment per service, descending, among all published procedure categories.

Immunizations, vaccinations, and therapeutic injections

91 procedures · Avg Medicare payment: $65.01

Code Procedure Medicare Billed
96372 Injection Of Drug Or Substance Under Skin Or Into Muscle $9.79 $54.48
90662 Influenza Vaccine Split Virus, Preservative Free $70.24 $89.29
90694 Influenza Vaccine, Quadrivalent Inactivated, 0.5 Ml Dosage $74.09 $88.01
95117 Professional Service For Multiple Injections Of Allergen $8.10 $35.07
90677 Pneumococcal Conjugate Vaccine, 20 Valent (pcv20), For Intramuscular Use $277.19 $418.18
96375 Injection Of Additional New Drug Or Substance Into Vein $12.09 $82.17
95115 Professional Service For Single Injection Of Allergen $6.66 $26.13
90686 Influenza Vaccine, Quadrivalent, Preservative Free, 0.5 Ml Dosage $21.38 $37.77
90674 Influenza Vaccine, Quadrivalent Derived From Cell Cultures, Preservative And Antibiotic Free $32.60 $46.28
90471 Administration Of Vaccine $12.65 $47.83
92235 Exam Of Retinal Blood Vessels Using A Special Camera After Injection Of A Dye $104.76 $294.39
96374 Injection Of Drug Or Substance Into Vein $29.25 $153.48
90732 Pneumococcal Vaccine, 23-Valent $127.78 $198.65
0240U Respiratory Infectious Agent Detection By Rna For Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19), Influenza A, And Influenza B) In Upper Respiratory Specimen, Each Reported As Detected Or Not Detected $139.71 $287.42
90688 Influenza Vaccine, Quadrivalent, 0.5 Ml Dosage $20.17 $43.42
0241U Respiratory Infectious Agent Detection By Rna For Severe Acute Respiratory Syndrome Coronavirus 2 (covid 19), Influenza A, Influenza B, And Respiratory Syncytial Virus, Upper Respiratory Specimen, Each Reported As Detected Or Not Detected $138.72 $288.21
90682 Influenza Vaccine, Quadrivalent Derived From Recombinant Dna $66.07 $83.94
90756 Influenza Vaccine, Quadrivalent Derived From Cell Cultures $30.95 $52.68
95874 Needle Measurement Of Electrical Activity In Muscle With Injection Of Chemical For Paralysis Of Nerve Muscle $43.65 $180.23
90715 Diphtheria, Tetanus, And Acellular Pertussis Vaccine (7 Years Or Older) $26.45 $83.87
90714 Diphtheria And Tetanus Vaccine (7 Years Or Older) $20.46 $61.79
90670 Pneumococcal Vaccine, 13-Valent $246.24 $390.26
90746 Hepatitis B Vaccine, Adult Dosage (3 Dose Schedule) $67.88 $138.93
96377 Application Of On-Body Injector For Under Skin Injection $14.43 $79.81
90671 Pneumococcal Conjugate Vaccine, 15 Valent (pcv15), For Intramuscular Use $238.51 $378.67
92242 Exam Of Retinal Blood Vessels And Blood Vessels Between The White Part Of Eye And Retina Using A Special Camera After Injection Of A Dye $206.42 $541.26
90472 Administration Of Vaccine, Each Additional Vaccine $9.14 $32.23
91304 Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Recombinant Spike Protein Nanoparticle, Saponin-Based Adjuvant, Preservative Free, 5 Mcg/0.5ml Dosage, For Intramuscular Use $142.52 $170.25
93352 Injection Of X-Ray Contrast During Ultrasound Of Heart $26.09 $136.93
90739 Hepatitis B Vaccine (hepb), Cpg-Adjuvanted, Adult Dosage, 2 Dose Or 4 Dose Schedule, For Intramuscular Use $146.78 $262.32
93567 Injection For Imaging Of Aorta Above Heart Valve With Review By Radiologist $29.86 $295.29
95180 Injection For Rapid Desensitization To Allergen $104.36 $333.19
92240 Exam Of Blood Vessels Between The White Part Of Eye And Retina Using A Special Camera After Injection Of A Dye $140.46 $562.59
92287 Imaging Of Front Third Of Eye Using A Special Camera After Injection Of A Dye $123.01 $330.90
95873 Electrical Stimulation For Guidance With Injection Of Chemical For Paralysis Of Nerve Muscle $38.83 $167.73
96373 Injection Of Drug Or Substance Into Artery $13.57 $85.47
0064A Intramuscular Administration Of Single Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Mrna-Lnp, Spike Protein, Preservative Free, 50 Mcg/0.25ml Dosage, Booster Dose $41.53 $67.82
93893 Ultrasound Of Within The Brain Blood Flow For Blood Clots With Microbubble Injection $77.42 $471.67
0004A Intramuscular Administration Of Single Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Mrna-Lnp, Spike Protein, Preservative Free, 30 Mcg/0.3ml Dosage, Diluent Reconstituted; Booster Dose $42.11 $65.92
0051A Intramuscular Administration Of Single Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Mrna-Lnp, Spike Protein, Preservative Free, 30 Mcg/0.3ml Dosage, Tris-Sucrose Formulation; First Dose $40.53 $72.14
90675 Rabies Vaccine For Injection Into Muscle $250.50 $584.06
0054A Intramuscular Administration Of Single Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Mrna-Lnp, Spike Protein, Preservative Free, 30 Mcg/0.3ml Dosage, Tris-Sucrose Formulation; Booster Dose $39.83 $53.52
0052A Intramuscular Administration Of Single Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Mrna-Lnp, Spike Protein, Preservative Free, 30 Mcg/0.3ml Dosage, Tris-Sucrose Formulation; Second Dose $40.50 $73.93
0011A Intramuscular Administration Of Single Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Mrna-Lnp, Spike Protein, Preservative Free, 100 Mcg/0.5ml Dosage; First Dose $39.94 $64.47
0013A Intramuscular Administration Of Single Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Mrna-Lnp, Spike Protein, Preservative Free, 100 Mcg/0.5ml Dosage; Third Dose $40.85 $72.14
96542 Injection Of Chemotherapy Via Reservoir Under Skin $45.53 $499.18
0012A Intramuscular Administration Of Single Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Mrna-Lnp, Spike Protein, Preservative Free, 100 Mcg/0.5ml Dosage; Second Dose $39.74 $64.89
0094A Intramuscular Administration Of Single Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Mrna-Lnp, Spike Protein, Preservative Free, 50 Mcg/0.5 Ml Dosage, Booster Dose $40.47 $56.38
0003A Intramuscular Administration Of Single Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Mrna-Lnp, Spike Protein, Preservative Free, 30 Mcg/0.3ml Dosage, Diluent Reconstituted; Third Dose $40.76 $80.12
93568 Injection For Nonselective Imaging Of Pulmonary Artery During Heart Catheterization $36.57 $402.47
90740 Hepatitis B Vaccine, Dialysis Or Immunosuppressed Patient Dosage $139.50 $230.65
0001A Intramuscular Administration Of Single Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Mrna-Lnp, Spike Protein, Preservative Free, 30 Mcg/0.3ml Dosage, Diluent Reconstituted; First Dose $39.57 $53.15
96379 Injection Or Infusion Into A Vein Or Artery For Therapy, Prevention, Or Diagnosis $93.90 $174.36
90375 Rabies Immune Globulin For Injection $230.31 $707.44
91300 Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Mrna-Lnp, Spike Protein, Preservative Free, 30 Mcg/0.3ml Dosage, Diluent Reconstituted, For Intramuscular Use $0.01 $9.62
91305 Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Mrna-Lnp, Spike Protein, Preservative Free, 30 Mcg/0.3ml Dosage, Tris-Sucrose Formulation, For Intramuscular Use $0.01 $6.23
91301 Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Mrna-Lnp, Spike Protein, Preservative Free, 100 Mcg/0.5ml Dosage, For Intramuscular Use $0.01 $12.95
93573 Injection For Selective Imaging Of Pulmonary Artery During Heart Catheterization, On Both Sides Of Body $50.01 $283.19
90620 Meningococcal Recombinant Protein And Outer Membrane Vesicle Vaccine, Serogroup B $165.91 $357.75
91309 Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Mrna-Lnp, Spike Protein, Preservative Free, 50 Mcg/0.5 Ml Dosage, For Intramuscular Use $0.01 $4.37
90865 Injection Of Hypnotic Drug For Psychiatric Diagnosis Or Therapy $106.98 $472.57
0053A Intramuscular Administration Of Single Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Mrna-Lnp, Spike Protein, Preservative Free, 30 Mcg/0.3ml Dosage, Tris-Sucrose Formulation; Third Dose $40.38 $80.61
0002A Intramuscular Administration Of Single Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Mrna-Lnp, Spike Protein, Preservative Free, 30 Mcg/0.3ml Dosage, Diluent Reconstituted; Second Dose $38.75 $54.25
0041A Intramuscular Administration Of Single Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Recombinant Spike Protein Nanoparticle, Saponin-Based Adjuvant, Preservative Free, 5 Mcg/0.5ml Dosage; First Dose $38.54 $50.86
0031A Intramuscular Administration Of Single Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Dna, Spike Protein, Adenovirus Type 26 (ad26) Vector, Preservative Free, 5x1010 Viral Particles/0.5ml Dosage; Single Dose $39.55 $61.44
90611 Smallpox And Monkeypox Vaccine, Attenuated Vaccinia Virus, Live, Non-Replicating, Preservative Free, 0.5 Ml Dosage, Suspension, For Subcutaneous Use $0.01 $0.48
90759 Vaccine For Hepatitis B (3 Dose Schedule) For Injection Into Muscle, 10 Mcg Dosage $70.31 $98.54
90747 Hepatitis B Vaccine, Dialysis Or Immunosuppressed Patient Dosage (4 Dose Schedule) $134.29 $282.56
0042A Intramuscular Administration Of Single Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Recombinant Spike Protein Nanoparticle, Saponin-Based Adjuvant, Preservative Free, 5 Mcg/0.5ml Dosage; Second Dose $38.57 $58.44
90653 Influenza Vaccine, Inactivated $58.13 $116.79
93569 Injection For Selective Imaging Of Pulmonary Artery During Heart Catheterization, On One Side Of Body $29.40 $245.50
90672 Influenza Vaccine, Quadrivalent For Nasal Administration $25.63 $41.14
91306 Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Mrna-Lnp, Spike Protein, Preservative Free, 50 Mcg/0.25ml Dosage, For Intramuscular Use $0.01 $2.81
90622 Vaccinia (smallpox) Virus Vaccine, Live, Lyophilized, 0.3 Ml Dosage, For Percutaneous Use $0.50 $82.72
93566 Injection For Imaging Of Right Heart Chambers With Review By Radiologist $20.70 $414.29
92230 Exam Of Retinal Blood Vessels Using An Endoscope After Injection Of A Dye $66.71 $173.57
90460 Administration Of First Vaccine Or Toxoid Component With Counseling (18 Years Or Younger) $16.20 $45.95
90377 Rabies Immune Globulin For Injection Beneath The Skin And/or Into Muscle $182.82 $455.97
93563 Injection For Imaging Of Coronary Blood Vessel During Evaluation Of Congenital Abnormalities With Review By Radiologist $40.51 $331.16
90632 Hepatitis A Vaccine Adult Dosage $46.72 $130.10
90744 Hepatitis B Vaccine, Pediatric Or Adolescent Dosage (3 Dose Schedule) $29.14 $75.38
90376 Rabies Immune Globulin For Injection Beneath The Skin And/or Into Muscle, Heat-Treated $204.82 $839.43
90687 Influenza Vaccine, Quadrivalent, 0.25 Ml Dosage $9.90 $30.08
90743 Hepatitis B Vaccine, Adolescent Dosage $64.79 $97.34
0034A Intramuscular Administration Of Single Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Dna, Spike Protein, Adenovirus Type 26 (ad26) Vector, Preservative Free, 5x1010 Viral Particles/0.5ml Dosage; Booster Dose $39.06 $45.55
93565 Injection For Imaging Of Left Heart Chambers With Review By Radiologist $21.45 $302.87
0071A Intramuscular Administration Of Single Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Mrna-Lnp, Spike Protein, Preservative Free, 10 Mcg/0.2ml Dosage, Diluent Reconstituted, Tris-Sucrose Formulation; First Dose $42.36 $63.31
93574 Injection For Selective Imaging Of Pulmonary Vein During Heart Catheterization $49.98 $474.94
91303 Severe Acute Respiratory Syndrome Coronavirus 2 (covid-19) Vaccine, Dna, Spike Protein, Adenovirus Type 26 (ad26) Vector, Preservative Free, 5x1010 Viral Particles/0.5ml Dosage, For Intramuscular Use $0.01 $2.26
90461 Administration Of Vaccine Or Toxoid Component With Counseling (18 Years Or Younger), Each Additional Vaccine Or Toxoid Component $7.56 $26.10
90371 Hepatitis B Immune Globulin For Injection Into Muscle $96.01 $282.53

Reading Vaccines & Injections Pricing Data

The 91 procedure codes grouped under Vaccines & Injections share a common clinical taxonomy in the CMS Medicare Physician & Other Practitioners dataset. Across this category, the average Medicare payment is $65.01 - the figure Medicare actually reimburses providers for the allowed amount after geographic and specialty adjustments. Immunizations, vaccinations, and therapeutic injections Each CPT/HCPCS code in the table above carries its own fee schedule value determined by CMS's Resource-Based Relative Value Scale (RBRVS), which weights physician work, practice expense, and professional liability.

Billed charges, the "Billed" column, often run several multiples above Medicare allowed amounts. This is expected under US chargemaster pricing practices: providers list a gross rate, then accept negotiated write-offs from Medicare, Medicaid, and commercial insurers under participation agreements. A high markup ratio does not necessarily indicate overcharging, because almost no payer pays the full billed charge. However, uninsured and out-of-network patients can be exposed to amounts closer to the billed rate, which is why federal rules now require providers to publish cash and negotiated prices through the Hospital Price Transparency initiative.

Volume matters when interpreting category-level data. Procedures with millions of annual services, evaluation visits, common diagnostic work, reflect stable, well-benchmarked pricing. Lower-volume codes may show wider variation across providers and settings because small sample sizes produce less stable averages. When comparing specific procedures, drill into the individual procedure page for state-level breakdowns, provider counts, and commercial pricing estimates derived from RAND 2024 research. This page presents CMS reference data for educational use; it does not constitute medical, legal, or financial advice.

Data sourced from the CMS Medicare Physician and Other Practitioners dataset. See our methodology for details. Retrieved and formatted by PlainProcedure  · Verify with CMS →

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from CMS (Centers for Medicare and Medicaid Services). Consult a qualified professional before making decisions based on this data.

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Every figure on PlainProcedure is rendered directly from CMS Medicare Physician & Other Practitioners data, no number is typed in by an editor. This page draws directly on CMS Medicare Physician & Other Practitioners data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.