2026 data Public-data reference. official source

Pathology

24 procedures in Pathology. Medicare reimbursement averages $519.75 per service; billed charges average N/A. Source: CMS Medicare Physician & Other Practitioners 2023.

Tissue examination, biopsies, and surgical pathology

24 procedures · Avg Medicare payment: $519.75

Code Procedure Medicare Billed
88305 Pathology Examination Of Tissue Using A Microscope,... $38.77 $184.28
88307 Pathology Examination Of Tissue Using A Microscope,... $69.73 $361.48
88304 Pathology Examination Of Tissue Using A Microscope,... $16.00 $110.43
81479 Molecular Pathology Procedure $2,324.97 $3,640.05
88321 Surgical Pathology Consultation And Report On Referred... $70.37 $321.57
88300 Pathology Examination Of Tissue Using A Microscope,... $3.90 $44.60
88309 Pathology Examination Of Tissue Using A Microscope,... $115.69 $551.41
88302 Pathology Examination Of Tissue Using A Microscope $6.98 $72.24
88323 Surgical Pathology Consultation And Report On Referred... $74.72 $294.54
80503 Pathology Clinical Consultation For Clinical Problem,... $17.38 $86.11
80506 Pathology Clinical Consultation, Additional 30 Minutes $33.23 $68.11
88325 Surgical Pathology Consultation And Report,... $120.27 $484.74
80505 Pathology Clinical Consultation For Complex Clinical... $70.93 $161.47
80504 Pathology Clinical Consultation For Moderately Complex... $36.34 $188.94
81400 Molecular Pathology Procedure Level 1 $62.59 $119.15
81503 Genetic Profiling On Oncology Biopsy Of Ovarian... $689.60 $1,491.58
81404 Molecular Pathology Procedure Level 5 $269.33 $317.96
81401 Molecular Pathology Procedure Level 2 $134.08 $412.83
81500 Genetic Profiling On Oncology Biopsy Of Ovarian... $200.39 $545.27
81554 Mrna Gene Analysis Of 190 Genes Associated With Lung... $5,399.69 $13,800.00
81405 Molecular Pathology Procedure Level 6 Genetic Analysis $295.32 $323.43
81406 Molecular Pathology Procedure Level 7 $282.14 $470.63
81403 Molecular Pathology Procedure Level 4 $181.50 $367.66
81408 Molecular Pathology Procedure Level 9 $1,960.00 $4,695.24

Reading Pathology Pricing Data

The 24 procedure codes grouped under Pathology share a common clinical taxonomy in the CMS Medicare Physician & Other Practitioners dataset. Across this category, the average Medicare payment is $519.75 — the figure Medicare actually reimburses providers for the allowed amount after geographic and specialty adjustments. Tissue examination, biopsies, and surgical pathology Each CPT/HCPCS code in the table above carries its own fee schedule value determined by CMS's Resource-Based Relative Value Scale (RBRVS), which weights physician work, practice expense, and professional liability.

Billed charges — the "Billed" column — often run several multiples above Medicare allowed amounts. This is expected under US chargemaster pricing practices: providers list a gross rate, then accept negotiated write-offs from Medicare, Medicaid, and commercial insurers under participation agreements. A high markup ratio does not necessarily indicate overcharging, because almost no payer pays the full billed charge. However, uninsured and out-of-network patients can be exposed to amounts closer to the billed rate, which is why federal rules now require providers to publish cash and negotiated prices through the Hospital Price Transparency initiative.

Volume matters when interpreting category-level data. Procedures with millions of annual services — evaluation visits, common diagnostic work — reflect stable, well-benchmarked pricing. Lower-volume codes may show wider variation across providers and settings because small sample sizes produce less stable averages. When comparing specific procedures, drill into the individual procedure page for state-level breakdowns, provider counts, and commercial pricing estimates derived from RAND 2024 research. This page presents CMS reference data for educational use; it does not constitute medical, legal, or financial advice.

Related

Data sourced from the CMS Medicare Physician and Other Practitioners dataset. See our methodology for details. Retrieved and formatted by PlainProcedure Editorial  · Verify with CMS →

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from CMS (Centers for Medicare and Medicaid Services). Consult a qualified professional before making decisions based on this data.

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